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Insulin Resistance

Insulin resistance occurs when the body’s cells stop responding effectively to insulin, the hormone that helps move glucose from the bloodstream into cells for energy.

As the body becomes less sensitive to insulin, the pancreas compensates by producing more, leading to chronically elevated insulin levels (hyperinsulinemia). Over time, this imbalance can cause rising blood sugar, setting the stage for prediabetes, type 2 diabetes, metabolic syndrome, and cardiometabolic disease.

For women, insulin resistance is especially important to understand because it is closely linked to midlife weight changes, hormonal shifts, PCOS, cardiovascular risk, and metabolic health. Many people have no symptoms until the condition progresses, making early awareness essential.

This tag includes guides, research summaries, and expert insights on what causes insulin resistance, how it’s diagnosed, and evidence‑based strategies shown to improve insulin sensitivity through lifestyle, nutrition, and clinical care.

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Brain & Cognition